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Researchers have devoted countless hours over the last year to develop a safe and effective vaccine. As we pass 500m vaccinations worldwide, let’s look back on the journey and how Stake traders invested in the scientists saving the world.

11 Feb 2020 the World Health Organisation recognises a mysterious and previously nameless killer. By the end of the week, Covid-19 was an infamously familiar name in every home, classroom, and office.

While panic, fear, and even suspicion took over, behind the scenes, teams of scientists and researchers took to the labs and began planning a solution for a problem that they didn’t yet understand.

Naturally, interest to invest in what was seen as a world-saving vaccine piqued. Investment in names like Pfizer, BioNTech, AstraZeneca, J&J, and Novavax soared.

In early March, the Solidarity Trial began. Covid infected patients were treated with existing medications. Drugs like Plaquenil (hydroxychloroquine) dominated headlines as a potential answer. Plaquenil manufacturer Solyn (SNY) saw an uptick in trade activity but most avoided the stock. By July, the WHO had discontinued all research into the drug.

The investment community was waiting for a specifically developed vaccine. Moderna (MRNA) was the first manufacturer to capture their attention. In the first two weeks of July, the stock rallied 50% on the back of positive phase 2 trial results and a coincidental Nasdaq 100 inclusion. Their preliminary vaccine showed antibody numbers 4x times greater than those found in recovered patients. Promising progress.

Thousands of Stake users traded US$8m worth of Moderna over this period. The stock had barely traded that much volume in the six months prior. To this day, Moderna remains Stake’s most traded “vaccine” stock with over US$50m in trade volume.

The coming months would prove the most pivotal if a vaccine were ever to become viable. The biggest vaccine manufacturers were engaging in the final stages of their trials.

By November, the results were in. Moderna reported a 94.1% efficacy rate; similarly, Pfizer’s vaccine posted a 95% rate. During this period, Moderna and Pfizer traded more than any other period on Stake, US$30m worth of stock was traded between the two.

The simple liberties we took for granted: borderless travel, dancefloors, and even hugs with loved ones were now looking realistic. While deployment could take years, there appeared to be a solution to the pandemic. Moderna rallied 100% during the month, Pfizer was up 20%, BioNTech gained 40%. Then came December.

December was a poignant reminder of the situation’s fragility.

On one side of the world, the CDC had approved several vaccines for deployment in the US. In the same week, a new strain of the virus was detected in South Africa. The discovery sucked optimism out of the markets as vaccine stocks began to tumble. Not only was this variant more contagious, but it could potentially evade vaccine-driven immunity. The major vaccines reported reduced efficacy against the strain as it spread to other parts of the world.

Thankfully, case numbers remain relatively low. On top of the South African strain, there are constantly new mutations developing worldwide. Scientists concede that this may mean a new vaccine is necessary annually. For now, the world is dealing with the biggest threat.

Three months into the new year, 550m doses have been administered worldwide. Keeping in mind that most vaccines require two injections, Israel leads the world with 115 doses per 100 people. The UAE, UK, Chile, and USA round out the top 5.

Vaccine stocks remain amongst the most popular on Stake, consistently trading in our top 100 even as the stocks edge into the green over the last month.


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Stakeshop Pty Ltd, trading as Stake, ACN 610105505, is an authorised representative (Authorised Representative No. 1241398) of Sanlam Private Wealth Pty Ltd (Australian Financial Services Licence No. 337927) ('Sanlam') and an authorised representative (Authorised Representative No. 1241398) of Airwallex Pty Ltd (Australian Financial Services Licence No. 487221) ('Airwallex'). Stake is not authorised by Airwallex under Airwallex’s AFSL to arrange for clients to be issued with securities as Airwallex is not authorised under its AFSL for this purpose. Stake is not authorised by Sanlam under Sanlam’s AFSL to arrange for clients to be issued with a non-cash payment facility as Sanlam is not authorised under its AFSL for this purpose. Stake SMSF Pty Ltd (‘Stake Super’) is not licensed to provide financial product advice under the Corporations Act. This specifically applies to any financial products which are established if you instruct Stake Super to set up a self managed super fund (‘SMSF’). When you sign up to Stake Super, you are contracting with Stake SMSF Pty Ltd who will assist in the establishment of a SMSF under a ‘no advice model’. You will also be referred to Stakeshop Pty Ltd to enable your trading account and bank account to be set up in order to use the Stake Website and/or App. Stakeshop Pty Ltd will also run marketing and promotions to you under. For more information about SMSFs, see our SMSF Risks page.The information on our website or our mobile application is not intended to be an inducement, offer or solicitation to anyone in any jurisdiction in which Stake is not regulated or able to market its services. At Stake and Stake Super, we’re focused on giving you a better investing experience but we don’t take into account your personal objectives, circumstances or financial needs. Any advice given by Stake is of a general nature only. As investments carry risk, before making any investment decision, please consider if it’s right for you and seek appropriate taxation and legal advice. Please view our Financial Services GuideTerms & ConditionsPrivacy Policy and Disclaimers  before deciding to invest on or use Stake or Stake Super. By using our website or service in any way, you agree to our Privacy Policy and Terms & Conditions. All financial products involve risk and you should ensure you understand the risks involved as certain financial products may not be suitable to everyone. Past performance of any product described on this website is not a reliable indication of future performance. Stake and Stake Super are registered trademarks in Australia.

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