Instil Bio, Inc.
Instil Bio, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing a cell therapy pipeline of autologous tumor infiltrating lymphocyte (TIL), therapies for the treatment of patients with cancer. The Company's lead TIL product candidate is ITIL-168, for the treatment of advanced melanoma. ITIL-168, is an autologous TIL therapy that is initially developing for the treatment of PD-1-inhibitor relapsed or refractory advanced melanoma. It is also developing a novel class of genetically engineered TIL therapies using its Co-Stimulatory Antigen Receptor (CoStAR) platform. Its lead CoStAR-TIL product candidate is ITIL-306, expresses a CoStAR molecule designed to recognize folate receptor alpha (FOLR1) a tumor-associated antigen that is expressed on numerous solid tumors, including ovarian cancer, uterine cancer, non-small cell lung cancer (NSCLC) and renal cancer.
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