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Spyre Therapeutics Inc

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About SYRE

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which is engaged in creating inflammatory bowel disease (IBD) and other immune-mediated disease products by combining antibody engineering, rational therapeutic combinations and precision medicine approaches. Its pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. Its pipeline programs include SPY003, SPY004, SPY130, SPY230, SPY002, SPY001, and SPY120. Its advanced product candidate, SPY001, is a fully human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD. Its co-lead program, SPY002, has nominated two fully human mAb candidates designed to bind to tumor necrosis factor-like ligand 1A (TL1A), both of which are in preclinical development for the treatment of IBD. SPY003 is a preclinical-stage program designed to bind to Interleukin 23 (IL-23) and incorporates half-life extending modifications.

Market Capitalisation

$2.61B

Price-earnings ratio

-

Dividend yield

0.00%

Volume

731.9K

High today

$35.17

Low today

$33.24

Open price

$34.36

52-week high

$35.31

52-week low

$10.91

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SYRE FAQs

Buying SYRE shares in Australia can be done through an online investing platform, such as Stake. Follow the simple steps below to start investing in Spyre Therapeutics Inc in minutes.
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The ticker symbol for Spyre Therapeutics Inc is SYRE.

One share of SYRE is valued at $33.51 as of 14 December 2025.

As of 14 December 2025 Spyre Therapeutics Inc has a market cap of $2.61B.

The Spyre Therapeutics Inc 52-week high stock price is $35.31.

The Spyre Therapeutics Inc 52-week low stock price is $10.91.

Yes, the Stake investing platform allows you to buy SYRE shares and over 9,500 more stocks and ETFs on Wall St.

This is not financial product advice nor a recommendation to invest in the securities listed. Past performance is not a reliable indicator of future performance. As always, do your own research and consider seeking financial, legal and taxation advice before investing. No representation is made as to the timeliness, reliability, accuracy or completeness of the market data provided.

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